Autoimmune Eye Diseases

Autoimmune disease sufferers often experience eye issues because the immune system targets the healthy parts of the eye.

Understanding autoimmune eye conditions

It is common for people with an autoimmune disease to experience eye issues. These problems arise because the immune system targets the healthy parts of the eye. Did you know, that about 1 person in 20 has an autoimmune disorder in New Zealand?

It is important to have regular eye tests if you have been diagnosed with an autoimmune condition including, but not limited to:

  • Rheumatoid arthritis.

  • Lupus.

  • Ankylosing spondylitis.

  • Sjogren’s syndrome.

  • Multiple sclerosis.

  • Thyroid disease.

This page will provide more information on autoimmune diseases, common symptoms, signs, diagnosis and treatment.

What is an autoimmune eye disease?

Your immune system is constantly working to destroy bacteria, viruses and other health threats. But sometimes it mistakenly targets your body’s own healthy cells ‑ this is known as an autoimmune disorder. Some of these disorders make the immune system attack cells in your eyes or the surrounding tissues. They can cause inflammation, dry eyes, vision problems and more.

Autoimmune disease and eye problems

Scientists have discovered more than 80 kinds of autoimmune disorders. Each of them affects the body in different ways. For example, psoriasis typically affects the skin, while Type 1 diabetes affects insulin production. 
 
Many of these disorders can also impact the eyes. For some autoimmune disorders, inflammation in or around the eyes is the first sign something's wrong. Other times, you can get a lot of symptoms affecting many different parts of your body. 
 
Immune disorders can be systemic (affecting many parts of the body) or organ‑specific.

1. Systemic autoimmune disorders

Some autoimmune disorders make the immune system attack many different parts of the body, including the eyes. Examples include rheumatoid arthritis, systemic sclerosis or lupus (SLE).

2. Eye‑specific autoimmune disease

Some autoimmune diseases mainly or only affect one part of the body, such as the eyes. For example, Sjogren's syndrome mainly affects the eyes and mouth.

Autoimmune eye condition symptoms

Different autoimmune diseases can affect the eyes in different ways. Unfortunately, the symptoms can easily be mistaken for other conditions, and people sometimes get misdiagnosed. This is why it’s important to have any changes in your eyes seen by an experienced specialist. 
 
Here are some common eye symptoms that may be caused by autoimmune diseases ‑ though not everyone will experience all of them. Be aware that this autoimmune eye disease list of symptoms isn't comprehensive, and some people get other symptoms too.

Red eyes

Some immune disorders, like rheumatoid arthritis, Crohn’s and Sjögren’s syndrome, can cause keratoconjunctivitis, making eyes and eyelids red or bloodshot. (See keratoconjunctivitis diagram below for more information.)
Learn more about red eye

Eye swelling

During an immune disorder flare‑up, conditions like Graves’ disease and Hashimoto’s thyroiditis can make your eyes and eyelids swell.

Dry eyes

Conditions like Sjögren’s syndrome, coeliac disease, Guillain‑Barré syndrome, Graves’ disease and psoriasis can affect your tears, making your eyes feel very dry. 
Learn more about dry eye syndrome

Eye pain

Immune disorders like rheumatoid arthritis can cause uveitis, which leads to a painful eye that’s sensitive to light. Multiple sclerosis can also cause a painful ache in the eye when you look around. 
Learn more about eye pain

Changes in vision

Conditions like diabetes, Graves’ disease, multiple sclerosis, lupus and Behçet’s disease can cause blurry or double vision, floaters, flashes or even sight loss. 
Learn more about diabetic retinopathy

Other symptoms

Eye problems can be the first sign of an immune disorder, like early eye inflammation in multiple sclerosis. Many people also get tiredness, joint pain, skin rashes, fevers and more.

Let’s get your vision sorted

Noticed your eyes hurting, or a change in your sight? Whether it’s something new or something that’s been bothering you for a while, we’re here to help.

Keratoconjunctivitis.

Learn more about this common symptom of autoimmune eye inflammation.

  1. 1 of 4

    Inflamed conjunctiva

    The conjunctiva is a clear layer covering the whites of your eyes. If the conjunctiva is inflamed, more blood goes to the area, causing 'pink eye'.

  2. 2 of 4

    Keratitis

    This is when the cornea, the clear window that covers your iris and pupil, gets inflamed.

  3. 3 of 4

    Watery eyes

    Your eyes might be more watery than usual.

  4. 4 of 4

    Blurry vision

    Your vision might change and things become blurry.

When your immune system affects your eyes

There are many autoimmune diseases that can affect vision. If you have an autoimmune condition and notice anything unusual with your eyes, it’s really important to get this checked by your GP, an optometrist, or a rheumatologist. Some autoimmune diseases can lead to serious eye problems if left untreated including, in rare cases, loss of sight.

Three women in business attire sit and stand around a desk in an office, discussing a printed chart with headshots and information.

Which autoimmune conditions can affect the eyes?

Many autoimmune diseases can cause eye problems. The following autoimmune eye disease list covers some of the common issues we see at our stores in New Zealand, but there are other disorders that can also affect your eyes.

Sjogren’s syndrome

Sjogren's syndrome is a chronic autoimmune disease that attacks the glands which keep your eyes moist and lubricated (it can also affect glands in your mouth and other parts of your body). It can make your eyes feel very dry. 
Learn more about dry eye syndrome

Graves’ disease

Graves’ disease is when the immune system attacks the thyroid gland, leading to an overproduction of thyroid hormones. For some people, it causes inflammation of muscles and tissues around the eyes which can result in bulging, puffy eyes.
Learn more about puffy eye

Multiple sclerosis (MS)

Multiple sclerosis (MS) is an autoimmune disease that affects the brain, spinal cord, and optic nerve. Optic neuritis (inflammation of the optic nerve in the eye) is a common symptom of MS. Other eye symptoms associated with MS include nystagmus and double vision. 
Learn more about double vision

Reiter’s syndrome

Reiter’s syndrome (also known as reactive arthritis) is a kind of inflammatory arthritis that affects the joints, eyes and urethra. It causes eye inflammation and can lead to conjunctivitis and uveitis (inflammation of the middle layer of the eye). 
Learn more about conjunctivitis

Rheumatoid arthritis

Many people think of rheumatoid arthritis as something that affects the joints, but it can also affect the eyes. It can cause dry eyes and inflammation of the whites of your eyes.

Behçet's disease

Bechet's disease is a systemic autoimmune disease that causes inflammation of blood vessels throughout your body ‑ including in the eyes. Many people with Bechet’s disease have autoimmune eye inflammation symptoms such as uveitis and retinal vasculitis (inflammation of the retinal blood vessels). 

Sarcoidosis

Sarcoidosis is a rare condition that makes small patches of red and swollen tissue called granulomas develop in the organs of the body. It usually affects the lungs, skin and eyes.

Let’s get your vision sorted

Noticed your eyes hurting, or a change in your sight? Whether it’s something new or something that’s been bothering you for a while, we’re here to help.

Diagnosing autoimmune eye problems

If you have symptoms of an autoimmune disease, it's really important to get diagnosed and treated as early as possible. This can help prevent the condition from getting worse and reduce the severity of your symptoms. 
 
Diagnosing autoimmune disorders can sometimes be challenging. This is because the symptoms are often mistaken for other health issues. 
 
If your GP suspects that your immune system is affecting your eyes, they may refer you to an eye specialist (optometrist or ophthalmologist), or to a specialist in immune conditions (rheumatologist or immunologist). These doctors will use different methods to get to the bottom of the issue.

At your eye test, the optometrist will investigate your eye health through the following ways:

Medical history

The doctor will want to know about when the symptoms began and ask information about what it feels like. They'll also ask about symptoms in other parts of your body.

OCT scan

This detailed eye scan shows damage to the retina or optic nerve, which can be linked to some immune disorders. Available in our stores across New Zealand. 
Learn more about OCT scans

Slit lamp examination

A slit lamp is a powerful microscope with a lamp attached. Again, it allows optometrists to closely inspect your eyes and spot signs of the immune system attacking healthy cells and tissues. 

Other ways to diagnose autoimmune issues...

Magnetic resonance imaging (MRI) scans, computed tomography (CT) scans and blood tests can also be helpful and can be arranged via your GP or medical specialist

Autoimmune eye disease treatment

If you have autoimmune disease eye symptoms, your GP or specialist will put together a treatment plan tailored to your needs. 
 
Some treatments will involve medical interventions, while others may focus on self‑care and home remedies to manage flare‑ups. Below are some of the most common treatment options for autoimmune‑related eye conditions.


Medical autoimmune eye disease treatments

Here are some of the common medical treatments that are used to treat autoimmune eye problems. It's important to be aware that different immune disorders may have very specialised treatments, so this isn't a complete list.

Anti‑inflammatories or corticosteroids

These medications reduce your immune system's inflammatory response. This can really help with calming down autoimmune eye inflammation. They can make flare‑ups less uncomfortable.


Ways you can help yourself if an autoimmune disease is impacting your eye health or vision...

Very often, simple home remedies and self‑care can help with managing flare‑ups of autoimmune disorders.

Sunglasses

If your eyes feel especially sensitive to light when you have a flare‑up, wearing sunglasses can help, particularly when spending time outdoors.

Artificial tears

Lubricating eye drops can ease dryness, discomfort and scratchiness during an autoimmune flare‑up.

Humidifiers

Again, if you have dry eyes, it can be helpful to use a humidifier. These devices release moisture into the air in your home. That means tears don't evaporate as quickly from your eyes.

Lifestyle choices

Good sleep, stress management, less alcohol and not smoking can help reduce flare‑ups and discomfort.

Regular eye appointments

By getting your eyes checked regularly by an optometrist, they'll be able to spot any changes in your eyes and give you advice on how to relieve many kinds of discomfort.

Common Autoimmune Eye Disorder Questions

Did you know?

AA Members are entitled to a free eye test (valued at $60), once every two years. Remember to present your AA Membership card in‑store.

Written with care and checked for accuracy

https://images.ctfassets.net/uuaxywrybmpn/1UdPSLjw3ixLDFogGKbOBK/184e62b368513327112e74f74c2cd2f7/Sarah_Halloran__1_.jpg

Sarah Halloran

B.VisSci, M.Optom

Sarah graduated from Queensland University of Technology in 2016 with a Masters of Optometry. She completed the Specsavers Graduate Program in 2018 and returned the following year as a mentor. Beyond this, Sarah has experience in ophthalmology practices in both cataract/refractive and retinal settings.

She also has experience in metro and regional stores while working as a locum. Sarah joined the Specsavers Support Office as a Clinical Performance Consultant in 2024 where she empowers and supports optometrists to deliver the best outcomes for their patients.

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